JOURNAL OF FEMALE
Objectives: The periurethral collagen injection was defended as
a safe and effective measure of treatment for stress urinary incontinence. This study was
conducted to determine the complications associated with a collagen transurethral
injection for the treatment of SUI in women. We report the incidence and conduct of the
From 1989, collagen treated with gluteraldehyde has been proposed as a treatment of Stress Urinary Incontinence (SUI ), mainly in the cases of instrinsic sphincter deficiency (ISD). The collagen is easy to be injected, it does not migrate to distant organs and has a low allergenic potential. It would have as an advantage in relation to other SUI treatments the simplicity of the execution of the method and the low incidence of adverse effects. The success rate varies from 68 to 94 % in the dependency of the technique used and the time of follow up 1,2,3. The main disadvantages of the method are the reduction of the efficiency in longer follow up and the high cost for the realization of the procedure. Stothers et al show the complications, however, might result from this method of treatment, particularly when there is a rigorous follow up. The complications however, have been, in their majority, transitory and not very significant with the exception of the urinary urgency with incontinence, present in 12.6% of the patients.
Aparecido Donizete Agostinho
1. MC GUIRE, E.J.; APPELL, R. Transurethral
collagen injection for urinary incontinence. Urology, v.43, p.413-5, 1994.
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